While there are three wineries located in the southern part of the state between Charleston and Savannah, most of South Carolina's wineries are located in the northern part of the state.
South Carolina wineries, regardless of their location, must contend with the state's difficult growing conditions to include high temperatures, high humidity, and fall hurricanes. Fruit wine as well as Muscadine, French-American hybrids, and vinifera are all being experimented with in an effort to find the varieties best suited for South Carolina's climate.
Tours typically last from 30 to 60 minutes per tour and they are well worth your time to check out the different ones. Each one has their own flavors, beauty, and charm to experience.
What is even more awesome is that most wineries offer free samples of their wines when you go through a tour as well. Some do more formal tasting events as well. The tours are extremely interesting and fun to do too. They aren't just there to sample the wine that you're looking forward to but are actually very informative and you get to meet a lot of like-minded people usually that are also doing the tour. It's always nice to a fellow wine lover! - Be sure to call ahead if you are planning on doing a tour at one of the wineries or vineyards though to check on availability since many of them get very busy during season.